This collaborative OSUN network course addresses topics that are of urgent global importance in our era of continuing discrimination, forced migration, socially sanctioned violence – and war. It promotes new teaching and thinking about the relationships among four distinct, but overlapping, historical, cultural, and political phenomena: antisemitism, the Holocaust, colonialism, and gender. Each of these terms becomes a lens through which to examine exclusion, prejudice, discrimination, race, and hate in their historical and contemporary manifestations. Each of these questions is widely discussed in its own setting, with antisemitism and the Holocaust studied separately from forms of racism rooted in colonial legacies. The aim of this course is to reframe such vital discussions that at present take place in parallel, and sometimes even in an antagonistic manner. The collaborating institutions will explore how we may use teaching, student engagement, and the nurturing of informed civic responsibility to clarify and work through these pressing intellectual tensions. Working collaboratively and dealing with the past and the present, faculty, and students will explore how we can comprehend and clarify intellectual conflicts which have real-world implications in diverse national and regional contexts. Students have an exciting opportunity for doing group work in the Holocaust and Genocide Centre in Johannesburg, thus developing their own ideas for virtual exhibitions and creative educational interventions.